In 1845, German immigrant, Dr. Joseph M. Reuss established a drug store under his name at the old seaport of Indianola. In 1872, learning the railroad would be built in Cuero, he opened a branch store in this city with his eldest son, Dr. August J. Reuss as operator. Following the 1875 hurricane, Dr. J.M. Reuss moved what was left of Indianola store and medical practice to Cuero and consolidated his business. He lived in Cuero until his death in 1908.
J.M. Reuss & Son Drug Store operated in the same building on Main Street in Cuero for 99 years. In 1971 Mr. Joe B. Reuss, great-grandson of Dr. J.M. Reuss moved the business to its present location at 515 N. Esplanade Street in Cuero. To preserve the many pieces of pharmacy memorabilia, a museum was incorporated into the new pharmacy's format.
	An antique soda fountain is the museum's centerpiece and was once the subject of the popular TV newsmagazine, "The Eyes of Texas". Many tourists visit the museum each year and learn not only a history of the pharmacy, but also a brief story of how our community originated.
This antique Coca-Cola dispenser is one of the most admired pieces in the exhibit. The Pharmacy Museum is open during regular business hours; Monday through Saturday, 8:30 A.M. to 6:00 P.M. (361) 275-3411 or (800) 444-3761